Two sample MR report
LGALS2_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.0300261 | 0.1342397 | 0.8293979 |
| Weighted median | 9 | 0.0562247 | 0.0218381 | 0.0100350 |
| Inverse variance weighted | 9 | 0.0544659 | 0.0169409 | 0.0013042 |
| Simple mode | 9 | 0.0637297 | 0.0311051 | 0.0746416 |
| Weighted mode | 9 | 0.0623224 | 0.0325225 | 0.0916386 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.8470335 | 7 | 0.9969338 |
| Inverse variance weighted | 1.2496032 | 8 | 0.9961272 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.054683 | 0.086185 | 0.5459342 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005596 | 0 | TRUE | 0.0243799 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
